
Thermo Fisher Scientific PDE2A Monoclonal Antibody (OTI5B10), TrueMAB
Human PDE2A 단백질을 인식하는 Mouse IgG2a 단클론 항체로, Western blot, ICC/IF, Flow cytometry에 사용 가능. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5B10 |
| Immunogen | Full length human recombinant protein of human PDE2A produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional round of desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
PDE2A (phosphodiesterase 2A) is a 100 kDa cyclic nucleotide phosphodiesterase with three isoforms (PDE2A1, PDE2A2, PDE2A3) arising from alternative splicing. It degrades both cAMP and cGMP, with higher efficacy for cGMP. PDE2A is highly expressed in the brain, particularly in the cerebellum and neocortex, and is associated with penile erectile dysfunction and regulation of endothelial cell barrier function.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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