Thermo Fisher Scientific RAE1 Polyclonal Antibody
RAE1 단백질을 인식하는 Thermo Fisher Scientific의 다클론 항체로, 인간에 반응하며 WB 및 IHC(P) 실험에 적합합니다. 합성 펩타이드 면역원 기반, 0.5 mg/mL 농도의 액상 형태로 제공되며, 연구용으로만 사용됩니다.
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- PA518401
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- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3–6 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (NAAEELKPRNKK) corresponding to the C-terminus amino acids of RAE1 (aa 357–368) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10988861 |
Product Specific Information
- Predicted to react with bovine, canine, mouse, porcine, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes result in accumulation of poly-containing mRNA in the nucleus, suggesting involvement in RNA export.
The human RAE1 protein, homologous to yeast Rae1, contains four WD40 motifs and localizes to nucleoplasmic foci, the nuclear rim, and cytoplasmic meshwork-like structures.
This gene is implicated in nucleocytoplasmic transport and may mediate attachment of cytoplasmic mRNPs to the cytoskeleton.
Alternatively spliced transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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