Thermo Fisher Scientific SH2D1A Polyclonal Antibody
SH2D1A 단백질을 인식하는 Thermo Fisher Scientific의 Goat Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합하며, 인간에 반응하고 마우스·랫에서 예측 반응. 0.5 mg/mL 농도의 액상 형태로, TBS/BSA buffer에 보존.
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (HKRYFRKIKN) corresponding to the internal amino acids of SH2D1A (aa 73–83) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11004586 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
The SH2D1A gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells.
This protein contains an SH2 domain and a short tail, and associates with the signaling lymphocyte-activation molecule (SLAM), acting as an inhibitor by blocking SHP-2 recruitment.
It also binds to other related surface molecules expressed on activated T, B, and NK cells, modulating signal transduction pathways.
Mutations in SH2D1A cause lymphoproliferative syndrome X-linked type 1 (Duncan disease), a rare immunodeficiency with extreme susceptibility to Epstein–Barr virus infection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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