Thermo Fisher Scientific 2-hydroxyisobutyryl-HIST1H2BC (Lys57) Polyclonal Antibody
Human HIST1H2BC (Lys57) 타깃의 폴리클로날 항체로, Rabbit IgG 기반. ICC/IF 및 ELISA에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 보관하며 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunocytochemistry (ICC/IF) | 1:10–1:100 | - |
| ELISA | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from Human Histone H2B type 1-C/E/F/G/I protein (53–64 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.15 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% ProClin 300 |
| Storage conditions | -20°C or -80°C if preferred |
| Shipping conditions | Wet ice |
| RRID | AB_2914940 |
Product Specific Information
Antibody tested in Indirect ELISA.
Target Information
Histones are basic nuclear proteins responsible for nucleosome structure in eukaryotic chromatin. Two molecules each of the four core histones (H2A, H2B, H3, H4) form an octamer, around which ~146 bp of DNA is wrapped to form nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes, promoting chromatin compaction into higher-order structures.
This protein also exhibits antibacterial and antifungal activity. The main transcript variant of this gene is intronless, encoding a replication-dependent histone H2B family member. It lacks a polyA tail and contains a palindromic termination element. The gene is located within the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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