Thermo Fisher Scientific CPT1A Recombinant Rabbit Monoclonal Antibody (3M6E9)
Thermo Fisher CPT1A 재조합 토끼 단클론 항체(3M6E9)는 인간 CPT1A 단백질을 인식하며 Western blot과 ELISA에 적합합니다. HEK293 세포에서 발현된 IgG 형식의 항체로, 높은 특이성과 재현성을 제공합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 3M6E9 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 520–720 of human CPT1A (NP_001867.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3093121 |
Product Specific Information
Immunogen sequence:
WDIPGECQEV IETSLNTANL LANDVDFHSF PFVAFGKGII KKCRTSPDAF VQLALQLAHY
KDMGKFCLTY EASMTRLFRE GRTETVRSCT TESCDFVRAM VDPAQTVEQR LKLFKLASEK
HQHMYRLAMT GSGIDRHLFC LYVVSKYLAV ESPFLKEVLS EPWRLSTSQT PQQQVELFDL
ENNPEYVSSG GGFGPVADDG YTarget Information
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (located in the outer membrane and detergent-labile) and carnitine palmitoyltransferase II (located in the inner membrane and detergent-stable), together with a carnitine-acylcarnitine translocase.
CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane, and its deficiency results in a decreased rate of fatty acid beta-oxidation.
Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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