Thermo Fisher Scientific PDE11A Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 712-933 of human PDE11A (NP_0586493) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PDE11A,uniProtId:Q9HCR9-1,ncbiNodeId:9606,antigenRange:712-933,antigenLength:933,antigenImageFileName:PA5-116660_PDE11A_Q9HCR9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-116660_PDE11A_Q9HCR9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.43 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2901291

Product Specific Information

Positive Samples: Mouse brain, Mouse testis, Mouse liver, Rat brain, Rat testis, Rat liver

Immunogen sequence: NNAFQAKSGS ALAQLYGTSA TLEHHHFNHA VMILQSEGHN IFANLSSKEY SDLMQLLKQS ILATDLTLYF ERRTEFFELV SKGEYDWNIK NHRDIFRSML MTACDLGAVT KPWEISRQVA ELVTSEFFEQ GDRERLELKL TPSAIFDRNR KDELPRLQLE WIDSICMPLY QALVKVNVKL KPMLDSVATN RSKWEELHQK RLLASTASSS PASVMVAKED RN

Target Information

The 3,5-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3,5-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5`-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.