Thermo Fisher Scientific GRAF Polyclonal Antibody
Thermo Fisher Scientific의 GRAF Polyclonal Antibody는 인간 ARHGAP26 단백질을 인식하는 rabbit polyclonal 항체입니다. Western blot과 IHC(P) 검증 완료. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer로 안정화되어 있습니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ARHGAP26. Recombinant protein control fragment (Product # RP-95487) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2790416 |
Product Specific Information
Immunogen sequence:
HLSRKKSSDS KPPSCSERPL TLFHTVQSTE KQEQRNSIIN SSLESVSSNP NSILNSSSSL QPNMNSSDPD LAVVKPTRPN SLPPNPSPTS
Target Information
Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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