Thermo Fisher Scientific SMC1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human SMC1 (aa801–1000). Validated for Western blot and immunocytochemistry. Unconjugated, liquid form at 0.5 mg/mL concentration. Suitable for multiple species including monkey, cat, pig, and bovine. For research u...
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- 720335
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Protein corresponding to human SMC1 (aa801–1000) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2663308 |
Product Specific Information
This antibody is predicted to react with Monkey, Cat, Pig, and Bovine.
Target Information
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair, and global transcriptional repression. These proteins are conserved in eukaryotes and are essential for proper mitotic chromosome segregation. The SMC1 and SMC3 proteins form a heterodimeric complex required for metaphase progression and sister chromatid cohesion. Mutations in the SMC1 gene can lead to Cornelia de Lange syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: 720335_SMC1_Q14683-1_Rabbit.svg, 720335_SMC1_Q14683-1_Rabbit_PDP.jpeg)
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