Thermo Fisher Scientific gamma Actin Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive controls: A431, NIH-3T3, JC, BCL-1, PC-12, Rat2
• Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (100%), Dog (96%), Chicken (100%), Chimpanzee (100%), Bovine (100%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Actins are highly conserved proteins involved in cell motility and cytoskeletal maintenance.
There are three main actin isoform groups in vertebrates: alpha, beta, and gamma.

• Alpha actins: Found in muscle tissues; major component of the contractile apparatus.
• Beta and gamma actins: Present in most cell types; mediate internal cell motility and cytoskeleton structure.
  Actin gamma 1, encoded by this gene, is a cytoplasmic actin found in all cell types.
  Mutations are linked to DFNA20/26 (autosomal dominant non-syndromic progressive hearing loss) and Baraitser-Winter syndrome.
  Alternative splicing results in multiple transcript variants.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.