Thermo Fisher Scientific DUSP22 Polyclonal Antibody
Thermo Fisher Scientific의 DUSP22 Polyclonal Antibody는 Human, Mouse, Rat에서 반응하며 Rabbit IgG 기반의 비결합 항체입니다. IHC, ICC/IF, ELISA 등 다양한 응용에 적합하며, Protein A로 정제된 고순도 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human DUSP22/JSP1, amino acids 13–100 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways activated by various stimuli, mediating numerous physiological and pathological cellular changes.
Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases.
DSP gene expression is induced by growth factors and/or cellular stresses, negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK, and p38.
DUSP22 dephosphorylates ERK2 MAP kinase and JNK, showing highest expression in thymus and detectable levels in monocytes and lymphocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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