Thermo Fisher Scientific HSD3B1 Polyclonal Antibody
HSD3B1 단백질을 인식하는 Thermo Fisher Scientific의 산양 유래 polyclonal 항체로, Western blot과 IHC(P)에서 검증됨. 합성 펩타이드 면역원 기반으로 높은 특이성과 민감도를 제공하며, 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.003–0.01 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3.75 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (DRHKETLKSKTQ) corresponding to the C-terminus amino acids of HSD3B1 (aa 362–373) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10980278 |
Product Specific Information
This antibody has been tested in Peptide ELISA with an antibody detection limit dilution of 1:128,000.
Target Information
Amyloid beta peptide (Abeta/Beta-amyloid) is the major constituent of amyloid plaques in the brains of individuals afflicted with Alzheimer’s disease. Abeta peptide is 40–43 amino acids long and generated from the beta-amyloid precursor protein (beta APP) in a two-step process. The first step involves cleavage of the extracellular, amino-terminal domain of beta APP by beta-secretase (BACE). The remnant protein is further processed by gamma-secretase, a multi-subunit complex containing presenilin-1 and -2, producing the amyloid beta peptide. Abeta is an extracellular filamentous protein component of amyloid cores and neuritic plaques, also found in neurofibrillary tangles. Beta amyloid deposits are characteristic of Alzheimer’s disease and are also detected in Lewy body dementia, Down’s syndrome, Dutch-type amyloidosis, cerebral amyloid angiopathy, and the Guam Parkinson-Dementia complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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