Thermo Fisher Scientific PFKFB3 Polyclonal Antibody
PFKFB3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 면역침강(IP)에 적합하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 1 mg/mL 농도, 4°C 보관, 연구용으로만 사용 가능.
- 카탈로그번호
- A304249A
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 470–520 of human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
The protein encoded by this gene belongs to a family of bifunctional enzymes involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a key regulator of glycolysis in eukaryotes.
It exhibits 6-phosphofructo-2-kinase activity (synthesis of F2,6BP) and fructose-2,6-biphosphatase activity (degradation of F2,6BP).
This protein is essential for cell cycle progression and apoptosis prevention, acting as a regulator of cyclin-dependent kinase 1 and linking glucose metabolism to cell proliferation and survival in tumor cells.
Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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