Thermo Fisher Scientific Relaxin 1/2 Polyclonal Antibody
Human Relaxin 1/2 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. KLH 결합 합성 펩타이드 면역원으로 제조되었으며, 고순도 Protein A 및 Antigen affinity chromatography로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 136–165 amino acids from the C-terminal region of human RLN1/RLN2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2717707 |
Target Information
Relaxins are endocrine and autocrine/paracrine hormones belonging to the insulin gene superfamily. In humans, there are three non-allelic relaxin genes: RLN1, RLN2, and RLN3, with RLN1 and RLN2 sharing high sequence homology.
The encoded protein is synthesized as a single-chain polypeptide, but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary and acts on the reproductive system to ripen the cervix, elongate the pubic symphysis, and inhibit uterine contraction.
It may also enhance sperm motility, regulate blood pressure, control heart rate, and stimulate the release of oxytocin and vasopressin.
Multiple alternatively spliced transcript variants are described for this gene, though their full-length nature is not fully known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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