Thermo Fisher Scientific CD73 Monoclonal Antibody (1D7)
CD73 단일클론 항체(1D7)는 인간 NT5E 단백질을 특이적으로 인식하며 WB, IHC, ICC 등 다양한 실험에 사용 가능. 비결합형 액상 형태로 제공되며 4°C 단기, -20°C 장기 보관 권장. 연구용으로 면역결핍 질환 관련 CD73 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 | View publication |
| Immunocytochemistry (ICC/IF) | 1:100 | View publication |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D7 |
| Immunogen | Purified recombinant fragment of NT5E expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term, store at -20°C and avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10981671 |
Product Specific Information
MA5-15537 targets NT5E in IHC applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of NT5E expressed in E. coli.
MA5-15537 detects NT5E, which has a predicted molecular weight of approximately 70 kDa.
Target Information
CD73 (Ecto-5'-nucleotidase, 5'-ribonucleotide phosphohydrolase) catalyzes the conversion of purine 5'-mononucleotides to nucleosides at neutral pH, with AMP as the preferred substrate.
CD73 is a dimer of two identical 70 kDa subunits bound to the plasma membrane via a glycosyl phosphatidylinositol linkage and serves as a marker of lymphocyte differentiation.
Deficiency of CD73 is associated with various immunodeficiency diseases.
The CD73 gene is localized to 6q14–q21 and defects may lead to joint and artery calcification or intestinal tuberculosis.
Two transcript variants encoding different isoforms of CD73 have been identified.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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