Thermo Fisher Scientific C14orf129 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human C14orf129. Recombinant protein control fragment (Product #RP-99852). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:C14orf129,uniProtId:Q9P0R6-1,ncbiNodeId:9606,antigenRange:70-134,antigenLength:139,antigenImageFileName:PA5-61322_C14orf129_Q9P0R6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-61322_C14orf129_Q9P0R6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2638754

Product Specific Information

Immunogen sequence: TKERNRYCLE LTEAGLKVVG YAFDQVDDHL QTPYHETVYS LLDTLSPAYR EAFGNALLQR LEALK

Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.

Target Information

This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.