Thermo Fisher Scientific SCD/SCD1/Stearoyl-CoA Desaturase Polyclonal Antibody
Rabbit polyclonal antibody targeting human Stearoyl-CoA desaturase (SCD/SCD1). Validated for WB and IP applications. Supplied as liquid, unconjugated, 1 mg/mL concentration. Recommended storage at 4 °C, shelf life 1 year. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 25 to 75 of Human Acyl-CoA desaturase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4 °C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, formed by desaturation of stearic acid. The ratio of stearic to oleic acid influences cell growth and differentiation through effects on membrane fluidity and signal transduction.
Four SCD isoforms (Scd1–Scd4) exist in mouse, while humans have two (SCD1 and SCD5). SCD1 shares ~85% amino acid identity with all four mouse SCD isoforms and with rat Scd1 and Scd2. SCD5, in contrast, shows limited homology with rodent SCDs and appears unique to primates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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