Thermo Fisher Scientific SCD/SCD1/Stearoyl-CoA Desaturase Polyclonal Antibody
SCD/SCD1 단백질 검출용 Thermo Fisher Scientific 폴리클로날 항체. Western blot 및 면역침강(IP)에 적합. 인간 반응성, 항원 친화 크로마토그래피 정제. 액상 형태, 1 mg/mL 농도, 4°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 25 to 75 of Human Acyl-CoA desaturase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
Target Information
Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, formed by desaturation of stearic acid. The ratio of stearic acid to oleic acid influences cell growth and differentiation through effects on membrane fluidity and signal transduction.
Four SCD isoforms (Scd1–Scd4) have been identified in mouse, while only two (SCD1 and SCD5) are found in human. SCD1 shares about 85% amino acid identity with all four mouse isoforms and with rat Scd1/Scd2. SCD5 shares limited homology with rodent SCDs and appears unique to primates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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