Thermo Fisher Scientific CNGB3 Polyclonal Antibody
Thermo Fisher Scientific의 CNGB3 Polyclonal Antibody는 인간 CNGB3 단백질을 인식하는 토끼 폴리클로날 항체입니다. Western blot 및 IHC에 적합하며, 합성 펩타이드를 면역원으로 사용했습니다. 동결 건조 형태로 제공되며 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human CNGB3 conjugated to blue carrier protein was used as the antigen |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: CNGB3.
Target Information
Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as a second messenger. This protein can be activated by cGMP, leading to the opening of the cation channel and causing depolarization of rod photoreceptors.
It induces flickering channel gating, weakens outward rectification in the presence of extracellular calcium, increases sensitivity for L-cis diltiazem, and enhances cAMP efficiency of the channel when coexpressed with CNGA3.
Essential for the generation of light-evoked electrical responses in red-, green-, and blue-sensitive cones.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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