Thermo Fisher Scientific CLCN7 Polyclonal Antibody
CLCN7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 적합하며, Human, Mouse, Rat 시료에서 반응. 동결건조 형태로 제공되며, 재구성 후 사용. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 5 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the N-terminal region of human Chloride channel protein 7 (CLCN7) conjugated to an immunogenic carrier protein. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: CLCN7.
Target Information
The CLCN7 gene encodes a chloride channel protein that belongs to the CLC chloride channel family. These channels are important in the plasma membrane and intracellular organelles.
Mutations in this gene cause osteopetrosis autosomal recessive type 4 (OPTB4), also known as infantile malignant osteopetrosis type 2, and autosomal dominant osteopetrosis type 2 (OPTA2), also called Albers-Schönberg disease or marble disease.
Osteopetrosis is a rare genetic disorder characterized by abnormally dense bone due to defective resorption of immature bone. OPTA2 is the most common form, typically occurring in adolescence or adulthood.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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