Thermo Fisher Scientific ACAT2 Polyclonal Antibody
ACAT2 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, IP 등 다양한 응용에 적합. 1 mg/mL 액상 형태로 제공되며 4°C에서 보관. FFPE 조직의 IHC 시 citrate buffer(pH 6.0) 전처리 권장.
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- A304293Ax (2개 옵션)
- 판매단위
- pk
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ACAT2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 | |
| Immunohistochemistry (IHC) | 1:500–1:2,000 | |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 150 to 200 of human Acetyl-CoA Acetyltransferase 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
Target Information
This gene represents a member of the frizzled gene family, which encodes 7-transmembrane domain proteins that are receptors for Wnt signaling proteins.
The protein encoded by this family member contains:
- A signal peptide
- A cysteine-rich domain in the N-terminal extracellular region
- Seven transmembrane domains
Unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif.
It functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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