Thermo Fisher Scientific Nrf2 Recombinant Rabbit Monoclonal Antibody (6W6R7)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

6W6R7

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 243-400 of human NRF2 (NP_006155.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Nrf2,uniProtId:Q16236-1,ncbiNodeId:9606,antigenRange:243-400,antigenLength:605,antigenImageFileName:MA5-51280_Nrf2_Q16236-1_Rabbit.svg,antigenImageFileNamePDP:MA5-51280_Nrf2_Q16236-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.93 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_3094332

Product Specific Information

Immunogen sequence: SPHFLNAFED SFSSILSTED PNQLTVNSLN SDATVNTDFG DEFYSAFIAE PSISNSMPSP ATLSHSLSEL LNGPIDVSDL SLCKAFNQNH PESTAEFNDS DSGISLNTSP SVASPEHSVE SSSYGDTLLG LSDSEVEELD SAPGSVKQNG PKTPVHSS

Target Information

Nfr1 (also designated TCF11), Nrf2 and Nfr3 are bZIP transcription factors that heterodimer with Maf proteins to bind MARE (Maf recognition elements) sequences. Nrf2 is widely expressed and is thought to translocate to the nucleus after treatment with xenobiotics and antioxidants, which stimulate its release from a repressor protein Keap1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.