Thermo Fisher Scientific H5N1 VN04-9 Monoclonal Antibody (7A11)
H5N1 인플루엔자 A 바이러스의 HA 단백질을 특이적으로 인식하는 단클론 항체. 다양한 클레이드의 H5N1 바이러스에 반응하며 교차 반응 없음. WB, IHC, ELISA, IP 등 다양한 응용 가능. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Assay-dependent
Immunohistochemistry (IHC)
- Assay-dependent
ELISA
- 1:5,000
Immunoprecipitation (IP)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7A11 |
| Immunogen | Concentrated purified virus preparation containing hemagglutinin (HA) protein of influenza A virus [strain A/Vietnam/1203/04 (H5N1)] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at -20°C prior to opening.
- Aliquot contents and freeze at -20°C or below for extended storage.
- Avoid cycles of freezing and thawing.
- Centrifuge product if not completely clear after standing at room temperature.
- Stable for several weeks at 4°C as an undiluted liquid.
- Dilute only prior to immediate use.
Specific for H5 hemagglutinin (HA) protein of influenza A virus [strain A/Vietnam/1203/04 (H5N1)].
VN04-9 monoclonal antibody did not cross-react with influenza viruses of other HA subtypes.
This monoclonal antibody reacted with H5N1 influenza viruses representing different clades and subclades of the H5 HA subtype.
Target Information
Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA.
In early 2009, a novel swine-origin influenza A (H1N1) virus was identified in specimens obtained from patients in Mexico and the United States.
The virus spread quickly around the world and on June 11, 2009, the World Health Organization declared it a pandemic.
Influenza A virus has:
- Sixteen possible Hemagglutinin (HA) surface proteins
- Nine possible Neuraminidase (NA) surface proteins
The Hemagglutinin protein facilitates viral attachment, while Neuraminidase is involved in viral release.
These proteins elicit immune responses that prevent infection or reduce viral replication.
The 2009 swine flu virus (H1N1) is genetically distinct from previous strains, combining human, swine, and avian influenza genes with additional pig H3N2 genes from Eurasia.
Its unique antigenic properties suggest limited human immunity, though older age groups may exhibit partial protection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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