Thermo Fisher Scientific Topoisomerase (DNA) I, Mitochondrial (TOP1MT) Monoclonal Antibody (TOP1MT/568)
사람 유래 미토콘드리아 DNA 토포이소머레이스 I(TOP1MT)을 인식하는 단클론 항체입니다. IHC(P) 및 IHC(PFA) 분석에 적합하며, 단백질 A/G로 정제된 액상 형태입니다. 보존제 없이 PBS(pH 7.4)에 보관하며, -20°C에서 냉동 보관합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TOP1MT/568 |
| Immunogen | Recombinant full-length human TOP1MT protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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