Thermo Fisher Scientific ATP2B1/2/3 Polyclonal Antibody
ATP2B1/2/3 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. Human, Mouse, Rat 시료에 반응하며, Affinity chromatography로 정제됨. PBS buffer에 50% glycerol 포함, -20°C 보관.
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ATP2B3 (Accession Q16720), corresponding to amino acid residues I1005–I1055 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815995 |
Product Specific Information
This antibody detects endogenous levels of total ATP2B1/2/3.
Target Information
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases, characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against large concentration gradients and play a critical role in intracellular calcium homeostasis.
Mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes, and diversity is further increased by alternative splicing. Expression of different isoforms and splice variants is regulated in a developmental, tissue-, and cell type-specific manner, suggesting functional adaptation to physiological needs. This gene encodes the plasma membrane calcium ATPase isoform 3.
주의사항
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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