Thermo Fisher Scientific 5T4 Monoclonal Antibody (524731)
인간 5T4 단백질을 인식하는 Mouse IgG1 단일클론 항체. IHC(P)에서 8–25 µg/mL로 사용 가능. 단백질 A/G로 정제된 동결건조 형태로 제공. PBS(5% 트레할로스) 완충액에 재구성 가능. 연구용으로만 사용.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 8–25 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 524731 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human 5T4 (Ser31–Ser355) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2607907 |
Product Specific Information
- In direct ELISAs, 100% cross-reactivity with recombinant mouse 5T4 is observed.
- Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion.
The encoded protein is an oncofetal antigen specific to trophoblast cells.
In adults, this protein is highly expressed in many tumor cells and is associated with poor clinical outcomes in numerous cancers.
Alternate splicing in the 5′ UTR results in multiple transcript variants that encode the same protein.
(Information provided by RefSeq, Oct 2009)
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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