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Thermo Fisher Scientific Phospho-Rb (Ser608) Polyclonal Antibody
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Rb 단백질의 Ser608 인산화 부위를 특이적으로 인식하는 Rabbit Polyclonal Antibody. IHC(P) 및 Dot blot에 적합하며, Protein A 및 항원 친화 크로마토그래피로 정제됨. 세포 성장 조절 및 암 관련 연구에 활용 가능.
- 카탈로그번호
- PA512679
- 판매단위
- pk
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마지막 업데이트 2025. 08. 05. 오후 09:17
카탈로그 번호 · 상품 설명출고판매가담기
Thermo Fisher Scientific PA512679 Phospho-Rb (Ser608) Polyclonal Antibody 400 ul pk판매 단위 pk ·
재고 확인 필요
660,800원VAT 포함 726,880원
Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-Rb (Ser608) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Dot blot (DB) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S608 of human RB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10985757 |
Target Information
Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription, and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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