Thermo Fisher Scientific SCG5 Polyclonal Antibody
SCG5 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간 단백질에 반응하며, 다양한 종에서 높은 상동성을 보입니다. 액상 형태로 제공되며, PBS와 sucrose buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human SCG5 (aa 70–119) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689851 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%
Target Information
Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway.
Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport to later compartments of the secretory pathway where it is proteolytically matured and activated.
Also required for cleavage of PCSK2 but does not appear to be involved in its folding.
Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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