Thermo Fisher Scientific RORB Monoclonal Antibody (1D1)
Human RORB 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB 및 ELISA에 적합합니다. GST 태그가 결합된 부분 재조합 단백질을 면역원으로 사용하며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, lambda |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D1 |
| Immunogen | RORB (NP_008845, 136–224 a.a) 부분 재조합 단백질 (GST 태그 포함, GST 태그 MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
ETSGTYANGH VIDLPKSEGY YNVDSGQPSP DQSGLDMTGI KQIKQEPIYD LTSVPNLFTY SSFNNGQLAP GITMTEIDRI AQNIIKSHL
Target Information
Retinoid-related orphan receptor beta (RORβ), a NR1 thyroid hormone receptor, influences development and function of the central nervous system, including sensory input integration and circadian timing.
Disruption of RORβ in mice leads to juvenile ataxia, retinal degeneration, circadian activity abnormalities, and delayed onset of male fertility.
RORβ binds to monomeric response elements containing the sequence AnnTAGGTCA as a monomer.
An alternatively spliced isoform, RORβ2, is found in the pineal gland and retina, sharing common DNA- and ligand-binding domains with wild-type RORβ but having a distinct amino-terminal domain.
Expression of RORβ has been documented in various regions of the mouse brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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