
Thermo Fisher Scientific KCNK10 (TREK-2) Polyclonal Antibody
Rabbit polyclonal antibody against KCNK10 (TREK-2), validated for Western Blot. Recognizes human and rat proteins. Lyophilized form, reconstitutable in DDW. Suitable for research on potassium channel function in kidney and pancreas.
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Applications
- Western Blot (WB): Tested dilution 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | TFRNYSLDEEKKEDETEKMC, corresponding to amino acid residues 475–494 of rat KCNK10 (Intracellular, C-terminal domain) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution: Add 50 µL or 0.2 mL double distilled water (DDW), depending on sample size.
The antibody is shipped as a lyophilized powder at room temperature and should be stored at -20°C upon arrival.
Reconstituted solution can be stored at 4°C for up to 1 week. For longer storage, aliquot and store at -20°C.
Avoid multiple freeze/thaw cycles. Centrifuge antibody preparations before use (10,000 × g, 5 min).
Target Information
KCNK10 (TREK-2) is a member of the potassium channel protein superfamily containing two pore-forming P domains.
It is highly expressed in the kidney and pancreas. This open rectifier channel primarily passes outward current under physiological K⁺ concentrations.
Activity is strongly stimulated by arachidonic acid and moderately by membrane stretching, intracellular acidification, and general anesthetics.
Three transcript variants have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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