Thermo Fisher Scientific HCN1 Polyclonal Antibody
Thermo Fisher Scientific의 HCN1 Polyclonal Antibody는 rat HCN1 단백질을 인식하는 구아니아피그 유래 IgG 항체입니다. Western blot 및 IHC에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 리오필라이즈 형태로 제공되며, 안정적인 저장 및 재구성 조건을 제공합니다.
- 카탈로그번호
- APC-056-GPxxxxx (3개 옵션)
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific HCN1 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:500
Immunohistochemistry (IHC)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host/Isotype | Guinea pig / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)KPNSASNSRDDGNSVYPSK, corresponding to amino acid residues 6–24 of rat HCN1, Intracellular, N-terminus |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.85 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: 25 µL, 50 µL, or 0.2 mL double distilled water (DDW), depending on sample size.
- Ships as a lyophilized powder at room temperature.
- Upon arrival, store at -20°C.
- Reconstituted solution can be stored at 4°C for up to 1 week.
- For longer storage, aliquot and store at -20°C.
- Avoid multiple freeze/thaw cycles.
- Centrifuge antibody preparations before use (10,000 × g, 5 min).
Target Information
HCN1 (Hyperpolarization-activated cation channel 1) is part of the HCN gene family contributing to spontaneous rhythmic activity in heart and brain.
HCN1 channels are activated by hyperpolarization and regulated by cyclic nucleotides. They play key roles in motor learning and neuronal integration, particularly in cerebellar Purkinje cells.
Expression is enriched in cerebral cortex, hippocampus, cerebellum, and facial motor nucleus.
Regional specificity among HCN channels contributes to differences in neuronal pacemaker activity across brain systems.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- APC-056-GP200UL_HCN1_Q9JKB0-1_Guinea_pig.svg
- APC-056-GP200UL_HCN1_Q9JKB0-1_Guinea_pig_PDP.jpeg
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