Thermo Fisher Scientific SETMAR Polyclonal Antibody
SETMAR 단백질을 인식하는 Thermo Fisher Scientific의 Polyclonal 항체로, Western blot에 최적화되어 있습니다. Human에 반응하며, Goat/IgG 기반 비결합형 항체입니다. 0.5 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관합니다.
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- PA518116
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (RWQKCVDCNGSYFD) corresponding to the C-terminus amino acids of SETMAR (aa 671–684) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10980966 |
Product Specific Information
- Predicted to react with bovine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
SETMAR (SET domain and mariner transposase fusion gene) is a histone methyltransferase that methylates Lys-4 and Lys-36 of histone H3, creating specific tags for epigenetic transcriptional activation.
It specifically mediates dimethylation of H3 Lys-36.
SETMAR has sequence-specific DNA-binding activity and recognizes the 19-mer core of the 5′-terminal inverted repeats (TIRs) of the Hsmar1 transposable element.
SETMAR also exhibits DNA nicking and in vivo end-joining activity, potentially mediating genomic integration of foreign DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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