Thermo Fisher Scientific CD299 (DC-SIGN/L) Polyclonal Antibody
CD299(CLEC4M/DC-SIGN/L) 단백질을 인식하는 Thermo Fisher Scientific의 토끼 다클론 항체로, Western blot, ICC/IF, ELISA에 사용 가능. 인간, 마우스, 랫트 반응성. 액상 형태로 -20°C 보관. 세포막 및 분비형 단백질 검출에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 71–399 of human CLEC4M (NP_0550723) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.065 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913834 |
Product Specific Information
- Positive test control: HepG2
- Subcellular localization: Cell membrane, Secreted, Single-pass type II membrane protein
Immunogen sequence:
QVSKVPSSLS QEQSEQDAIY QNLTQLKAAV GELSEKSKLQ EIYQELTQLK AAVGELPEKS KLQEIYQELT RLKAAVGELP EKSKLQEIYQ ELTRLKAAVG ELPEKSKLQE IYQELTRLKA AVGELPEKSK LQEIYQELTE LKAAVGELPE KSKLQEIYQE LTQLKAAVGE LPDQSKQQQI YQELTDLKTA FERLCRHCPK DWTFFQGNCY FMSNSQRNWH DSVTACQEVR AQLVVIKTAE EQNFLQLQTS RSNRFSWMGL SDLNQEGTWQ WVDGSPLSPS FQRYWNSGEP NNSGNEDCAE FSGSGWNDNR CDVDNYWICK KPAACFRDE
Target Information
CLEC4M is a type II integral membrane protein that shares 77% identity with CD209 antigen, a known HIV gp120-binding protein. Similar to CD209, CLEC4M binds intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, enhancing HIV-1 infection of T cells.
This gene is located on chromosome 19p13.3, within a cluster containing CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been identified, though the biological relevance of some remains uncertain.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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