Thermo Fisher Scientific UBR4 Polyclonal Antibody
UBR4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Human, Mouse, Rat 시료에 반응하며, IHC(P)에서 1:100–1:200 희석으로 사용 가능. PBS 기반 용액 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용.
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Applications
- Immunohistochemistry (Paraffin) [IHC (P)]: 1:100–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human UBR4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.6 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2688400 |
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
E3 ubiquitin-protein ligase that is a component of the N-end rule pathway. Recognizes and binds to proteins with destabilizing N-terminal residues, leading to ubiquitination and degradation. Forms meshwork structures with clathrin involved in membrane morphogenesis and cytoskeletal organization. Regulates integrin-mediated signaling and may activate FAK in response to cell-matrix interactions. Mediates ubiquitination of ACLY, resulting in its degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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