Thermo Fisher Scientific FCER2 Monoclonal Antibody (OTI2B6), TrueMAB
인간 FCER2(CD23)에 특이적인 단클론 항체로, Western blot, IHC, Flow cytometry 등 다양한 응용 가능. 마우스 IgG1 형식의 TrueMAB 제품이며, 고순도 친화 크로마토그래피 정제. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | Assay-Dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 48–321 of human FCER2 produced in SF9 cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD23 is a 45 kDa glycoprotein present on a subpopulation of freshly isolated peripheral blood and tonsil B cells, and is strongly expressed on EBV-transformed B lymphoblasts.
The CD23 molecule is identical to the low affinity IgE receptor found on B cells.
Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocytic leukemia and some cases of centroblastic/centrocytic lymphoma.
Functionally, CD23 is involved in B cell growth and differentiation and IgE production.
A soluble form of CD23 acts as a potent mitogenic factor.
Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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