
Thermo Fisher Scientific GPR143 Polyclonal Antibody
Rabbit polyclonal antibody against human GPR143 (OA1) for WB and IHC. Recognizes ocular albinism type 1 protein. Lyophilized form, reconstitute with distilled water. Suitable for research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | View 1 publication |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
Product Specifications
| Property | Description |
|---|---|
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the 3rd cytoplasmic domain of human GPR143 (OA1) conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Conditions | Store at 4 °C short term. For long-term storage, store at −20 °C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2113654 |
Product Specific Information
- Reconstitute with 100 µL of distilled water.
- Centrifuge to remove any insoluble material.
Target Information
Ocular albinism type 1 protein (GPR143) is a conserved integral membrane protein with seven transmembrane domains. It is expressed in the eye and epidermal melanocytes. Defects in GPR143 cause ocular albinism type 1 (OA1), also known as Nettleship-Falls type ocular albinism. OA1 is an X-linked disorder characterized by severe visual impairment, retinal hypopigmentation, and the presence of macromelanosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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