Thermo Fisher Scientific Ric-8A Polyclonal Antibody
Rabbit polyclonal antibody against Ric-8A, suitable for Western blot and immunoprecipitation. Recognizes region 418–468 of human Ric-8A. Predicted to react with rat, bovine, and orangutan. Supplied as liquid, 1 mg/mL, stored at 4°C.
- 카탈로그번호
- A304572Ax (2개 옵션)
- 판매단위
- pk
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Ric-8A Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 418 to 468 of Human Resistance to Inhibitors of Cholinesterase 8 Homolog A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, and Orangutan
Target Information
Guanine nucleotide exchange factor (GEF), which can activate some but not all G-alpha proteins. Able to activate GNAI1, GNAO1, and GNAQ, but not GNAS, by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release of G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex. Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing G(q)-coupled receptor-mediated ERK activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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