Thermo Fisher Scientific Ric-8A Polyclonal Antibody
Human 및 Mouse 시료에 반응하는 Ric-8A 폴리클로날 항체로 Western blot 및 Immunoprecipitation에 적합. Rabbit IgG 기반, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 4°C 보관, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 418–468 of Human Resistance to Inhibitors of Cholinesterase 8 Homolog A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
- Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, and Orangutan.
Target Information
Guanine nucleotide exchange factor (GEF) that can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1, and GNAQ, but not GNAS, by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic chromosome movement by stimulating G(i)-alpha protein, possibly leading to release of G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex. Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing G(q)-coupled receptor-mediated ERK activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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