Thermo Fisher Scientific USP11 Polyclonal Antibody
USP11 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot 및 Immunocytochemistry에 적합. 인간, 마우스, 랫트 반응성. 고순도 Affinity chromatography 정제, 액상 형태로 -20°C 보관. 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human USP11 (Accession P51784), corresponding to amino acid residues I221–L271 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851373 |
Product Specific Information
This antibody detects endogenous levels of total USP11.
Target Information
USP11 (ubiquitin specific peptidase 11), also known as UHX1, is a 920 amino acid deubiquitinating enzyme that participates in the ubiquitin pathway. Localized to the nucleus, USP11 associates with Ran BP-M (Ran binding protein M) and the tumor suppressor BRCA2. Through these interactions, USP11 inhibits ubiquitination or removes ubiquitin residues from these proteins. USP11 is implicated in several X-linked retinal diseases and may play a role in tumor suppression due to its ability to deubiquitinate BRCA2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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