Thermo Fisher Scientific BAK Recombinant Rabbit Monoclonal Antibody (7Q3T8)
BAK 단백질을 표적하는 재조합 토끼 단클론 항체로, WB, IHC, ELISA에 적용 가능. 인간 및 생쥐 반응성. HEK293 세포에서 발현된 IgG 형 항체. 고순도의 친화 크로마토그래피 정제 제품으로 연구용에 적합.
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Thermo Fisher Scientific BAK Recombinant Rabbit Monoclonal Antibody (7Q3T8)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 7Q3T8 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 11–82 of human Bak (NP_001179.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.089 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3093805 |
Product Specific Information
Immunogen sequence:
RQECGEPALP SASEEQVAQD TEEVFRSYVF YRHQQEQEAE GVAAPADPEM VTLPLQPSST MGQVGRQLAI IG
Target Information
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators involved in a wide variety of cellular activities.
This protein localizes to mitochondria and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, leading to a loss in membrane potential and release of cytochrome c.
It also interacts with the tumor suppressor P53 after exposure to cell stress.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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