Thermo Fisher Scientific NPY Polyclonal Antibody
Neuropeptide Y(NPY)에 특이적인 염소 다클론 항체로, WB 및 IHC(P/F)에서 사용 가능. 사람, 마우스, 토끼, 랫, 제노푸스에 반응. 동결건조 형태로 제공되며 보존제를 포함하지 않음. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:3,000 | - |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:300–1:3,000 | - |
| Immunohistochemistry (Frozen) (IHC-F) | 1:300–1:3,000 | - |
| Miscellaneous PubMed (Misc) | - | View 4 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rabbit, Rat, Xenopus |
| Published Species | Not Applicable |
| Host / Isotype | Goat / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 20–70 of mouse NPY (Neuropeptide Y) conjugated to an immunogenic carrier protein. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 150 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The antigen is homologous in many species including human, rat, zebrafish, and xenopus.
- Specificity: NPY (Neuropeptide Y).
Target Information
Neuropeptide Y (NPY) is a neuropeptide widely expressed in the central nervous system. It influences cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. NPY acts through G protein-coupled receptors to inhibit adenylyl cyclase, activate MAP kinase, regulate intracellular calcium, and activate potassium channels.
A polymorphism causing a leucine-to-proline substitution at position 7 in the signal peptide is linked to elevated cholesterol levels, higher alcohol consumption, and may increase risk for metabolic and cardiovascular diseases.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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