
Thermo Fisher Scientific ADH5 Monoclonal Antibody (OTI4H3), TrueMAB
ADH5 단백질을 인식하는 Mouse monoclonal 항체로, Western blot에 최적화되어 있습니다. Human, Mouse, Rat에 반응하며, Lyophilized 형태로 제공됩니다. PBS buffer에 보관하며, 연구용으로 formaldehyde 대사 관련 연구에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4H3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–266 of human ADH5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The ADH5 gene encodes a member of the alcohol dehydrogenase family. These enzymes metabolize a wide range of substrates including ethanol, retinol, aliphatic alcohols, hydroxysteroids, and lipid peroxidation products.
The encoded protein forms a homodimer and exhibits high activity for oxidation of long-chain primary alcohols and S-hydroxymethyl-glutathione, a formaldehyde-glutathione adduct.
This enzyme plays a key role in formaldehyde detoxification, protecting cells from irritant and sensitizing effects such as lacrymation, rhinitis, and dermatitis.
The human genome contains several non-transcribed pseudogenes related to ADH5.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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