Thermo Fisher Scientific PDLIM3 Polyclonal Antibody
PDLIM3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot에 사용 가능. 인간에 반응하며, 마우스·랫트·돼지 등에도 예측 반응. 항원 친화 크로마토그래피로 정제된 액상 시약으로, 연구용에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 302–364 of Human PDLIM3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.75 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2546107 |
Product Specific Information
- Recommended positive control: PDLIM3-transfected 293T cells
- Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Rhesus Monkey (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The PDLIM3 protein contains both PDZ and LIM domains, suggesting a role in cytoskeletal assembly. It binds the spectrin-like repeats of alpha-actinin-2 and colocalizes with alpha-actinin-2 at the Z lines of skeletal muscle. Although located near a region of chromosome 4 associated with facioscapulohumeral muscular dystrophy, this gene itself is not implicated in the disease. Two transcript variants encoding different isoforms have been identified.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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