Thermo Fisher Scientific XPA Polyclonal Antibody
XPA 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin) 실험에 적합. 인간 및 마우스 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 연구용 전용 제품.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human XPA (Accession P23025), corresponding to amino acid residues H171–K221 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900770 |
Product Specific Information
Antibody detects endogenous levels of total XPA.
Target Information
The XPA (xeroderma pigmentosum group A) protein specifically recognizes UV- or chemically damaged DNA lesions and triggers the nucleotide excision repair process.
XPA binds to replication protein A (RPA) or excision repair cross complementing 1 protein (ERCC1).
In the absence of nucleotide excision repair, persisting unrepaired DNA lesions may lead to accumulation of mutations and ultimately to cancer.
Xeroderma pigmentosum patients have a >2000-fold increased risk of developing skin cancer at sun-exposed areas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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