Thermo Fisher Scientific CD3 Monoclonal Antibody (CT-3), Biotin
CD3 단백질을 표적하는 Biotin 결합 단클론 항체로, 조류 및 닭 시료에서 Flow Cytometry에 적합합니다. CT-3 클론 기반으로 제작되었으며, 고순도 정제된 액상 형태로 제공됩니다. PBS 완충액에 0.1% 미만의 sodium azide를 포함하고 4°C에서 보관합니다.
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Applications
- Flow Cytometry (Flow): 1 µg/10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Avian, Chicken |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CT-3 |
| Immunogen | Chicken thymocytes and Ig⁻ blood mononuclear cells |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.4 |
| Contains | <0.1% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745654 |
Additional Formats
Target Information
The CD3 subunit complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and regulating TCR complex expression. CD3 subunits (gamma, delta, epsilon, zeta) are part of the immunoglobulin superfamily and encoded by genes on human chromosome 11. They contain cytoplasmic tails associated with signal transduction molecules via tyrosine-based motifs. CD3 plays roles in TCR-induced growth arrest, survival, and proliferation. It is expressed on 68–82% of normal peripheral blood lymphocytes, 65–85% of thymocytes, and Purkinje cells, but not on B or NK cells. Defects in CD3 genes are linked to CD3 immunodeficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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