Thermo Fisher Scientific NEDD4 Recombinant Rabbit Monoclonal Antibody (23GB2255)
NEDD4 단백질을 인식하는 토끼 유래 재조합 단클론 항체로, Western blot, ICC/IF, Flow cytometry에 사용 가능. 인간, 마우스, 랫트 반응성. HEK293F 발현, Affinity chromatography로 정제. -20°C 보관, 연구용 전용.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB2255 |
| Immunogen | A synthesized peptide derived from human NEDD4 (1271–1319 AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The E3 ubiquitin-protein ligase NEDD4 is a Ubl conjugation pathway protein containing one HECT (E6AP-type E3 ubiquitin-protein ligase) domain and four WW domains. It participates in the degradation pathway of VEGFR-2/KDFR, independent of its ubiquitin-ligase activity.
NEDD4 acts as a potential proto-oncogene by negatively regulating PTEN through ubiquitination, analogous to the Mdm2–p53 relationship. It is also involved in viral budding and regulates epithelial Na⁺ channels, contributing to arterial hypertension.
NEDD4 localizes to the sarcolemmal region of muscle fibers; its increased expression is associated with muscle unloading and denervation, as well as decreased Notch1 expression, thus acting as a downregulator of Notch-1 gene expression.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific FosB Recombinant Rabbit Monoclonal Antibody (23GB2285)
296,200원
Thermo Fisher Scientific
Thermo Fisher Scientific SF3B3 Recombinant Rabbit Monoclonal Antibody (23GB2260)
296,200원
Thermo Fisher Scientific
Thermo Fisher Scientific NEDD4 Recombinant Rabbit Monoclonal Antibody (23GB2255)
296,200원
Thermo Fisher Scientific
Thermo Fisher Scientific DNMT3A Recombinant Rabbit Monoclonal Antibody (23GB2230)
296,200원
Thermo Fisher Scientific
Thermo Fisher Scientific PLA2G2A Recombinant Rabbit Monoclonal Antibody (23GB2190)
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|