Thermo Fisher Scientific IARS2 Polyclonal Antibody
Thermo Fisher Scientific의 IARS2 Polyclonal Antibody는 인간, 생쥐, 랫트에 반응하는 Rabbit IgG 항체입니다. Western blot, IHC(P), ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용되며 장기 보관 시 -20°C에서 보관하십시오.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human IARS2. Recombinant protein control fragment (Product #RP-94008). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2642607 |
Product Specific Information
Immunogen sequence:
ALNGMVEMMD RRPYWCISRQ RVWGVPIPVF HHKTKDEYLI NSQTTEHIVK LVEQHGSDIW WTLPPEQLLP KEVLSEVGGP DALEYVPGQD
Highest antigen sequence identity to the following orthologs:
- Mouse: 86%
- Rat: 84%
Target Information
The Trip230 gene encodes a protein of 1,978 amino acids with an estimated molecular mass of 230 kDa.
The gene is located on chromosome 14q31, which is associated with genetic alterations and thyroid hormone response abnormalities.
Trip230 interacts with Rb and thyroid hormone receptor (TR) using two distinct domains.
Complex formation with Rb occurs in a hormone-independent manner, while complex formation with TR is thyroid hormone-dependent.
After T3 treatment, Trip230 is phosphorylated and transported to the nucleus, suggesting phosphorylation is important for nuclear translocation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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