Thermo Fisher Scientific IARS2 Polyclonal Antibody
Human IARS2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS(40% glycerol) 버퍼에 보존. 연구용 전용 제품으로 높은 특이성과 재현성을 제공.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human IARS2 (Recombinant protein control fragment: Product #RP-94007) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642606 |
Product Specific Information
Immunogen sequence:
VASQHNLPMD CLVDEDGVFT DVAGPELQNK AVLEEGTDVV IKMLQTAKNL LKEEKLVHSY PYDWRTKKPV VIRASKQWFI NITDIKTA
Sequence identity with orthologs:
- Mouse: 83%
- Rat: 81%
Target Information
The Trip230 gene encodes a protein of 1,978 amino acids with an estimated molecular mass of 230 kDa. It is located on chromosome 14q31, a region associated with genetic alterations and thyroid hormone response abnormalities. The Trip230 protein interacts with Rb and thyroid hormone receptor (TR) using distinct domains. Complex formation with Rb occurs in a hormone-independent manner, while interaction with TR is thyroid hormone-dependent. After T3 treatment, Trip230 is phosphorylated and translocated to the nucleus, suggesting phosphorylation is important for nuclear translocation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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