Thermo Fisher Scientific ATF1 Monoclonal Antibody (OTI7H3)
ATF1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot 및 IHC(Paraffin)에서 검증됨. 인간 시료 반응성, Mouse IgG2a 아이소타입. 액상 형태, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7H3 |
| Immunogen | Full length human recombinant protein of ATF1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723936 |
Target Information
This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It regulates downstream target genes involved in growth, survival, and other cellular activities. The protein is phosphorylated at serine 63 by various kinases, enhancing its transcriptional activity and contributing to cell transformation. Gene fusions with FUS (chromosome 16) or EWSR1 (chromosome 22) generate chimeric proteins implicated in angiomatoid fibrous histiocytoma and clear cell sarcoma. A pseudogene exists on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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