Thermo Fisher Scientific PDE4A Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 325-410 of human PDE4A (NP_0011047771) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PDE4A,uniProtId:P27815-1,ncbiNodeId:9606,antigenRange:325-410,antigenLength:886,antigenImageFileName:PA5-116927_PDE4A_P27815-1_Rabbit.svg,antigenImageFileNamePDP:PA5-116927_PDE4A_P27815-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2901557

Product Specific Information

Positive Samples: HeLa, K-562, SH-SY5Y, Mouse testis, Mouse brain, Mouse heart, Rat testis, Rat brain

Immunogen sequence: PVPHLQPMSQ ITGLKKLMHS NSLNNSNIPR FGVKTDQEEL LAQELENLNK WGLNIFCVSD YAGGRSLTCI MYMIFQERDL LKKFRI

Target Information

Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. Cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. PDE4A is a class IV cAMP-specific PDE.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.