Thermo Fisher Scientific SLFN12 Polyclonal Antibody
Human SLFN12 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 ELISA에 사용 가능. Affinity chromatography로 정제되었으며, PBS 및 50% glycerol 용액에 보관. 세포 성장 및 T세포 분화 연구에 적합.
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- PA5116929
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 320–390 of human SLFN12 (NP_001275938.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.08 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901559 |
Product Specific Information
- Positive Samples: SH-SY5Y
- Immunogen sequence:
DSWHVKDNRV MQLTRKEWIQ FMVEAEPKFS SSYEEVISQI NTSLPAPHSW PLLEWQRQRH HCPGLSGRIT Y
Target Information
The Schlafen (SLFN) family of proteins is preferentially expressed in lymphoid tissues and differentially regulated during thymocyte maturation. SLFN proteins are thought to play roles in cell growth, hematopoietic cell differentiation, and T cell development and maturation. Most SLFN members contain at least one divergent AAA domain (AAA_4) that may be involved in ATP binding. Human SLFN12, although sometimes referred to as SLFN3, has relatively low homology to SLFN3 in other species. Deletion of the SLFN12 gene is associated with Kabuki syndrome, suggesting a functional role in this genetic condition.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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