Thermo Fisher Scientific SLFN12 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Positive Samples: SH-SY5Y
• Immunogen sequence:
  DSWHVKDNRV MQLTRKEWIQ FMVEAEPKFS SSYEEVISQI NTSLPAPHSW PLLEWQRQRH HCPGLSGRIT Y

Target Information

The Schlafen (SLFN) family of proteins is preferentially expressed in lymphoid tissues and differentially regulated during thymocyte maturation. SLFN proteins are thought to play roles in cell growth, hematopoietic cell differentiation, and T cell development and maturation. Most SLFN members contain at least one divergent AAA domain (AAA_4) that may be involved in ATP binding. Human SLFN12, although sometimes referred to as SLFN3, has relatively low homology to SLFN3 in other species. Deletion of the SLFN12 gene is associated with Kabuki syndrome, suggesting a functional role in this genetic condition.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.